Hannes Mikula

Short-CV

After finishing his studies in Technical Chemistry and following a 1-year career break (2012-2013, paternity leave), Hannes received his Ph.D. from TU Wien in 2014. Fascinated and inspired by the emerging field of bioorthogonal chemistry, he then joined the lab of Prof. Ralph Weissleder at the Massachusetts General Hospital & Harvard Medical School as a postdoctoral fellow supported by an FWF Schrödinger Fellowship. In 2016, Hannes returned to TU Wien as a young principal investigator and since 2018 he is leading the group ‘Molecular Chemistry & Chemical Biology’ at the Institute of Applied Synthetic Chemistry. From 2021 to 2022 he was Assistant Professor (Laufbahnstelle, Tenure Track) and after completing the process of ‘Habilitation’ (venia docendi) became Associate Professor in January 2023. Since October 2023, Hannes is University Professor of Chemical Biology (full professorship). His team mainly focuses on the development of molecular tools and technologies for bioorthogonal chemistry, chemical biology, diagnostic and therapeutic strategies.

After finishing his studies in Technical Chemistry and following a 1-year career break (2012-2013, paternity leave), Hannes received his Ph.D. from TU Wien in 2014. Fascinated and inspired by the emerging field of bioorthogonal chemistry, he then joined the lab of Prof. Ralph Weissleder at the Massachusetts General Hospital & Harvard Medical School as a postdoctoral fellow supported by an FWF Schrödinger Fellowship. In 2016, Hannes returned to TU Wien as a young principal investigator and since 2018 he is leading the group ‘Molecular Chemistry & Chemical Biology’ at the Institute of Applied Synthetic Chemistry. From 2021 to 2022 he was Assistant Professor (Laufbahnstelle, Tenure Track) and after completing the process of ‘Habilitation’ (venia docendi) became Associate Professor in January 2023. Since October 2023, Hannes is University Professor of Chemical Biology (full professorship). His team mainly focuses on the development of molecular tools and technologies for bioorthogonal chemistry, chemical biology, diagnostic and therapeutic strategies.


RESEARCH INTERESTS

  • Bioorthogonal Chemistry
    Development of new chemical tools and reactions to advance the field of click, bioorthogonal & in vivo chemistry; Enhancing bioorthogonal tools by unraveling the underlying molecular mechanisms
  • Diagnostic tools - in vitro assays
    Design of substrates, methods and strategies for LC-MS/MS based diagnostics (e.g. newborn screening of rare diseases), and development of assays for therapeutic drug monitoring (e.g. 'last resort' antibiotics)
  • Diagnostic tools - in vivo medical imaging
    New diagnostic imaging strategies based on in vivo click chemistry (pretargeted molecular imaging, development of bioorthogonal tools radiolabeled with PET nuclides, e.g.fluorine-18)
  • Bioorthogonal drug targeting strategies
    Development of new paradigms to safely and selectively deliver and/or activate drugs in target tissue/cells by applying new bioorthogonal strategies
  • Radiotheranostics
    Combination of diagnostic and therapeutic radionuclides to design bioorthgonal theranostic strategies
  • Bioorthogonal Chemistry
    Development of new chemical tools and reactions to advance the field of click, bioorthogonal & in vivo chemistry; Enhancing bioorthogonal tools by unraveling the underlying molecular mechanisms
  • Diagnostic tools - in vitro assays
    Design of substrates, methods and strategies for LC-MS/MS based diagnostics (e.g. newborn screening of rare diseases), and development of assays for therapeutic drug monitoring (e.g. 'last resort' antibiotics)
  • Diagnostic tools - in vivo medical imaging
    New diagnostic imaging strategies based on in vivo click chemistry (pretargeted molecular imaging, development of bioorthogonal tools radiolabeled with PET nuclides, e.g.fluorine-18)
  • Bioorthogonal drug targeting strategies
    Development of new paradigms to safely and selectively deliver and/or activate drugs in target tissue/cells by applying new bioorthogonal strategies
  • Radiotheranostics
    Combination of diagnostic and therapeutic radionuclides to design bioorthgonal theranostic strategies

AWARDS & FELLOWSHIPS

  • 2023   Elisabeth Lutz Award, Austrian Academy of Sciences (ÖAW)
  • 2023   European Young Group Leader Award of the Chemical Biology Division of the Spanish Royal Society of Chemistry (RSEQ)
  • 2022   ERC Starting Grant, ERC-2021-STG, European Research Council (ERC)
  • 2021   START Award, Austrian Science Fund (FWF)
  • 2020   Science Award (Wissenschaftspreis), Austrian Chemical Society (GÖCH) & Austrian Academy of Sciences (ÖAW)
  • 2019   Dream Chemistry Top 5 Award, IOCB Prague & IChF-PAN
  • 2019   ASciNA Young Scientist Award, ASciNA & Federal Ministry of Education, Science and Research, Austria
  • 2015   Karl Schlögl Award, Austrian Academy of Sciences (ÖAW)
  • 2015   Postdoctoral Award (Habilitationspreis), Austrian Chemical Society (GÖCH)
  • 2014   Schrödinger Fellowship, Austrian Science Fund (FWF)
  • 2014   Promotio sub auspiciis Praesidentis rei publicae (PhD with highest distinction)
  • 2014   Excellence Scholarship, Federal Ministry of Science, Research and Economy, Austria
  • 2014   PhD Thesis Award (Dissertationspreis), Austrian Chemical Society (GÖCH)
  • 2014   Appreciation Award (Würdigungspreis), Federal Ministry of Science, Research and Economy, Austria
  • 2013   T. Kery Award, Kery Foundation, Burgenland, Austria
  • 2011   T. Körner Award, Theodor Körner Fund, presented by the Federal President of Austria
  • 2008   Diploma Thesis Award of the City of Vienna, Austria
  • 2023   Elisabeth Lutz Award, Austrian Academy of Sciences (ÖAW)
  • 2023   European Young Group Leader Award of the Chemical Biology Division of the Spanish Royal Society of Chemistry (RSEQ)
  • 2022   ERC Starting Grant, ERC-2021-STG, European Research Council (ERC)
  • 2021   START Award, Austrian Science Fund (FWF)
  • 2020   Science Award (Wissenschaftspreis), Austrian Chemical Society (GÖCH) & Austrian Academy of Sciences (ÖAW)
  • 2019   Dream Chemistry Top 5 Award, IOCB Prague & IChF-PAN
  • 2019   ASciNA Young Scientist Award, ASciNA & Federal Ministry of Education, Science and Research, Austria
  • 2015   Karl Schlögl Award, Austrian Academy of Sciences (ÖAW)
  • 2015   Postdoctoral Award (Habilitationspreis), Austrian Chemical Society (GÖCH)
  • 2014   Schrödinger Fellowship, Austrian Science Fund (FWF)
  • 2014   Promotio sub auspiciis Praesidentis rei publicae (PhD with highest distinction)
  • 2014   Excellence Scholarship, Federal Ministry of Science, Research and Economy, Austria
  • 2014   PhD Thesis Award (Dissertationspreis), Austrian Chemical Society (GÖCH)
  • 2014   Appreciation Award (Würdigungspreis), Federal Ministry of Science, Research and Economy, Austria
  • 2013   T. Kery Award, Kery Foundation, Burgenland, Austria
  • 2011   T. Körner Award, Theodor Körner Fund, presented by the Federal President of Austria
  • 2008   Diploma Thesis Award of the City of Vienna, Austria


PUBLICATIONS


Head of Research Group

Hannes Mikula

Hannes Mikula

hannes.mikula@tuwien.ac.at

Getreidemarkt 9/163
Room BI01G10
1060 Vienna